- Barker's Hypothesis (1995), a.k.a. Fetal Origin Hypothesis, states that fetal undernutrition in middle to late gestation (the period during which the embryo develops) not only leads to disproportional fetal growth, but also programmes for coronary heart disease later in life.
- Nutrients and oxygen level have been known to have influence on babies who are born small (i.e. lesser growth).
- Nutrients related to brain development: protein, iron (related to production of enzyme), zinc, copper, long-chain polyunsaturted fatty acid and choline.
- Lack of iron can cause the network of nerve cells in the brain to be cut short, so impulses or messages cannot be connected or send effectively. So iron deficiency affects the child's brain.
- What can negatively affect fetal brain's iron status? Low maternal iron supply, low placental iron transfer and high fetal iron demand.
- The first 2 years of a child's life is when brain development is increased, but after 2 years, the brainwave slows down.
- Multiple micronutrient supplementation showed positive effect in non-verbal intelligence rather than verbal intelligence.
Stay tuned for Part 6!